AMORPHOUS VARENICLINE TARTRATE CO-PRECIPITATES
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United States of America Patent
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Issued Date -
Apr 19, 2012
app pub date -
Jun 9, 2010
filing date -
Jun 10, 2009
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Abandoned
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Abstract
Disclosed herein is a stable amorphous coprecipitate comprising varenicline tartrate and a pharmaceutically acceptable excipient selected from the group consisting of maltodextrin, lactose monohydrate and 2-hydroxypropyl-β-cyclodextrin, method for the preparation, pharmaceutical compositions, and method of treating thereof. Advantageously, the amorphous coprecipitates of varenicline tartrate disclosed herein have improved physiochemical characteristics that assist in the effective bioavailability.
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