VIBRATING MICROPLATE BIOSENSING FOR CHARACTERISING PROPERTIES OR BEHAVIOUR OF BIOLOGICAL CELLS
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United States of America Patent
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Issued Date -
Mar 29, 2012
app pub date -
Jun 25, 2010
filing date -
Jun 30, 2009
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Abandoned
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Abstract
There is described a method of characterising a property or behaviour of at least one biological cell. The method comprises the steps of: providing a microplate; submerging at least one surface of the microplate in a cell culture medium such that at least one biological cell to be characterised is in contact with the microplate; vibrating the microplate; providing a plurality of mutually spaced sensors coupled to the microplate; obtaining a respective sensory data time series from each sensor during vibration of the microplate, the microplate and the sensors being arranged such that the obtained sensory data time series are not independent from one another; and processing the sensory data time series so as to characterise a property or behaviour of the at least one biological cell. A corresponding system for characterising a property or behaviour of at least one biological cell is also described.
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