POORLY SOLUBLE DRUG CONTAINING MICROSPHERE WITH IMPROVED BIOAVAILABILTY AND METHOD OF PREPARING THE SAME
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United States of America Patent
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Issued Date -
Mar 29, 2012
app pub date -
May 27, 2010
filing date -
May 27, 2009
priority date (Note) -
Abandoned
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Abstract
A poorly soluble drug containing microsphere with improved bioavailability, an oral formulation comprising the same, and a method of preparing the same are provided, wherein the poorly soluble drug containing microsphere is a solid dispersion wherein the poorly soluble drug is dispersed in the water-soluble polymer carrier in a noncrystalline form by spray drying, thus increasing bioavailability of the poorly soluble drug.
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