IDENTIFICATION AND CHARACTERIZATION OF RACEMASES, DEFINITION OF PROTEIN SIGNATURES, AND A TEST FOR DETECTING D-AMINO ACID AND FOR SCREENING MOLECULES CAPABLE OF INHIBITING THE ACTIVITY OF RACEMASE, ESPECIALLY PROLINE RACEMASE

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United States of America Patent

APP PUB NO 20120076815A1
SERIAL NO

12895268

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Abstract

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This invention provides identification and characterization of racemases and definition of protein signatures of these racemases. This invention also provides identification of nucleic acid molecules encoding a peptide consisting of a motif characteristic of the protein signatures, and to the peptides consisting of these motifs. Antibodies specific for the peptides and to immune complexes of these antibodies with the peptides are also provided. Further, the invention relates to methods and kits for detecting racemases using the nucleic acid molecules of the invention, as well as the peptides consisting of the motifs and antibodies to these peptides.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT PASTEUR28 RUE DU DOCTEUR ROUX 75724 PARIS CEDEX 15 FRANCE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berneman, Armand Paris, FR 13 40
Chamond, Nathalie Paris, FR 8 2
Degrave, Wim M Rio de Janeiro, BR 5 3
Minoprio, Paola Villiers sur Marne, FR 12 16

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