Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides
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United States of America Patent
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Issued Date -
Mar 22, 2012
app pub date -
Feb 11, 2010
filing date -
Feb 11, 2009
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Abstract
The invention relates to the provision of compounds, methods for producing them, and their use for imaging and quantification of aggregates of β-amyloid peptides in vivo. In a preferred aspect of the invention, a tracer is administered to humans and displays enrichment in body parts that are containing aggregates of amyloid peptides. Tracers of the invention can be used for non-invasive depiction and quantification of aggregates of β-amyloid peptides in humans affected with diseases that are characterized in the generation of such aggregates.
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