Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide

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United States of America Patent

SERIAL NO

13301068

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Abstract

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Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield.

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Patent Owner(s)

Patent OwnerAddress
ACTAVIS GROUP PTC HFREYKJAVIKURVEGI 76-78 220 HAFNARFJORDUR

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alapharthi, Madhubabu Bangalore, IN 2 0
Balla, Venkata Sasidhar Bangalore, IN 2 0
Pradhan, Nitin Sharadchandra Maharashtra, IN 63 171
Valgeirsson, Jon Hafnarfjorour, IS 32 36

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