AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF

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United States of America Patent

SERIAL NO

13227922

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns heparanase inhibiting compounds of general formula (I) wherein R represents a hydrogen atom, an hydroxyl radical, a —OSO3— radical, a —O—(C1-C5)alkyl radical or an —O— aralkyl radical; Z represents a COO radical or a hydroxyl radical; X represents —OH or a saccharide unit of formula A, Y represents H, C1-C5 alkyl or a saccharide unit of formula D; in free form or in the form of pharmaceutically acceptable salts formed with a base or an acid as well as in the form of solvates or hydrates. The derivatives of the invention are useful as medicines.

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Patent Owner(s)

Patent OwnerAddress
SANOFI-AVENTISPARIS FRANCE PARIS PARIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DRIGUEZ, Pierre Alexandre Toulouse, FR 7 40
PETITOU, Maurice Paris, FR 46 770

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