POLYMERIC PHARMACEUTICAL DOSAGE FORM IN SUSTAINED RELEASE
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United States of America Patent
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Issued Date -
Mar 15, 2012
app pub date -
Nov 30, 2009
filing date -
Nov 30, 2008
priority date (Note) -
Abandoned
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Abstract
This invention relates to a polymeric pharmaceutical dosage form for the delivery, in use, of at least one pharmaceutical composition in a rate-modulated and site-specific manner. The dosage form comprises a biodegradable, polymeric, scaffold incorporating loaded with at least one active pharmaceutical ingredient (API). The polymer or polymers making up the scaffold degrade in a human or animal body in response to or in the absence of specific biological stimuli and, on degradation, release the API or APIs in an area where said stimuli are encountered. Preferably the polymeric scaffold is formed from poly (D1L-lactide) (PLA) and polymethacrylate (Eudragit S100/ES100) polymers.
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