VIBRATION INDUCED IN VIVO SUBSTANCE TARGETING
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United States of America Patent
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Issued Date -
Mar 8, 2012
app pub date -
Sep 7, 2011
filing date -
Sep 7, 2010
priority date (Note) -
Abandoned
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Abstract
A method for aggregating a substance in a localized region within a body of an animal comprises applying a vibration pattern that causes aggregation of the substance to the localized region within the body of the animal, introducing the substance and aggregating the substance in the localized region based upon application of the vibration pattern. The substance, which may be a drug, fluorescent dye, conjugate of the two or a smart probe, may aggregate to bone, specifically to the lumbar region of the spine. About two to about four times more substance may aggregate in the localized region of the body relative to a control where no vibration pattern is applied.
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