Administration of HB-EGF for the Protection of Enteric Neurons
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United States of America Patent
Stats
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N/A
Issued Date -
Mar 1, 2012
app pub date -
Aug 31, 2010
filing date -
Aug 31, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention provides for methods of protecting neurons within the enteric nervous system (ENS) comprising administering an EGF receptor agonist, such as heparin-binding EGF (HB-EGF). These methods include reducing damage of ENS neurons in patient s suffering from an intestinal injury. In addition, the invention provides for increasing intestinal motility in a patient suffering from an intestinal injury comprising administering HB-EGF. The invention also provides for methods of inducing neurite growth within the ENS in a patient suffering from intestinal injury comprising administering HB-EGF.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
NATIONWIDE CHILDREN'S HOSPITAL INC | COLUMBUS OH 43205 |
International Classification(s)

- 2010 Application Filing Year
- A61K Class
- 10962 Applications Filed
- 7633 Patents Issued To-Date
- 69.64 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
BESNER, GAIL E | DUBLIN, US | 19 | 111 |
# of filed Patents : 19 Total Citations : 111 | |||
ZHOU, YU | UPPER ARLINGTON, US | 454 | 2834 |
# of filed Patents : 454 Total Citations : 2834 |
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Patent Citation Ranking
- 8 Citation Count
- A61K Class
- 12.01 % this patent is cited more than
- 13 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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