ASSAY FOR DETECTION OF ADRENAL TUMOUR
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United States of America Patent
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Feb 16, 2012
app pub date -
Feb 16, 2010
filing date -
Feb 16, 2009
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The invention relates to methods, assays and kits for detecting or monitoring adrenal tumours by detecting one or more adrenal steroid metabolites. The metabolites are selected from THS (tetrahydro-11-desoxycortisol), 5-PT (5-pregnenetriol), 5-PD (pregnenediol), PD (pregnanediol), PT (pregnanetriol), Et (etiolanolone), TH-DOC (tetrahydro-11-corticosterone), (5α-THA) 5α-tetra-11-hydrocorticosterone, and 5α-THF (5α-tetra hydrocortisol. An (Androsterone) may also be measured. 6β-OH-cortisol may be measured to monitor mitotane therapy.
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