ASSAY FOR DETECTION OF ADRENAL TUMOUR

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United States of America Patent

APP PUB NO 20120040332A1
SERIAL NO

13138431

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to methods, assays and kits for detecting or monitoring adrenal tumours by detecting one or more adrenal steroid metabolites. The metabolites are selected from THS (tetrahydro-11-desoxycortisol), 5-PT (5-pregnenetriol), 5-PD (pregnenediol), PD (pregnanediol), PT (pregnanetriol), Et (etiolanolone), TH-DOC (tetrahydro-11-corticosterone), (5α-THA) 5α-tetra-11-hydrocorticosterone, and 5α-THF (5α-tetra hydrocortisol. An (Androsterone) may also be measured. 6β-OH-cortisol may be measured to monitor mitotane therapy.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF BIRMINGHAM THEP O BOX 363 EDGBASTON BIRMINGHAM B15 2

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arlt, Wiebke Birmingham, GB 3 1
Stewart, Paul Michael Solihull, GB 2 52

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