PHARMACEUTICAL COMPOSITION FOR TREATING CANCER COMPRISING CHLORIN E6-FOLIC ACID CONJUGATE COMPOUND AND CHITOSAN

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United States of America Patent

APP PUB NO 20120035180A1
SERIAL NO

12594180

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Abstract

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The present invention relates to a pharmaceutical composition for the treatment of cancer comprising a chlorin e6-folic acid conjugate compound and chitosan, and more particularly, to a pharmaceutical composition for photodynamic therapy of solid tumors comprising the novel chlorin e6-folic acid conjugate compound or a pharmaceutically acceptable salt thereof and chitosan, in which the novel compound is prepared by linking chlorin e6 to folic acid, and effectively produces singlet oxygen in various media and has much better tumor selectivity than the known porphyrin-based photosensitizers, thereby being used effectively in photodynamic treatment for malignant tumors.

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Patent Owner(s)

Patent OwnerAddress
DIATECH KOREA CO LTDSONGPA-GU SEOUL 138-200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Hyo Jun Busan, KR 30 62
Lee, Eun Hee Gyeonggi-do, KR 17 56
Park, Kye Shin Seoul, KR 3 7

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges842417611114322011046329171032401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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