AGENT FOR SUPPRESSING REPLICATION OF HIV AND USE THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America Patent

SERIAL NO

13146440

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

It is an object of the present invention to provide an agent for suppressing the replication of HIV, which comprises a human CD4-recognizing antibody. The object is solved by an agent for suppressing the replication of human immunodeficiency virus, which comprises, as an active ingredient, an antibody described in (1) below:(1) an antibody recognizing human CD4, which comprises, as the amino acid sequence of the variable region of a heavy chain thereof, the amino acid sequence shown in SEQ ID NO: 2 in the sequence listing, or an amino acid sequence having at least one type of mutation selected from the group consisting of deletion, substitution, inversion, addition and insertion of one or multiple amino acids with respect to the amino acid sequence shown in SEQ ID NO: 2 in the sequence listing; and which also comprises, as the amino acid sequence of the variable region of a light chain thereof, the amino acid sequence shown in SEQ ID NO: 4 in the sequence listing, or an amino acid sequence having at least one type of mutation selected from the group consisting of deletion, substitution, inversion, addition and insertion of one or multiple amino acids with respect to the amino acid sequence shown in SEQ ID NO: 4 in the sequence listing.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
TOKAI UNIVERSITY EDUCATIONAL SYSTEMTOKYO JAPAN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Takekoshi, Fumiko Kanagawa, JP 1 1
Takekoshi, Masataka Kanagawa, JP 1 1

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation