METHODS AND APPARATUS FOR ACOUSTIC TREATMENT OF SAMPLES FOR HEATING AND COOLING
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United States of America Patent
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Issued Date -
Feb 2, 2012
app pub date -
Jul 28, 2011
filing date -
Jul 28, 2010
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Abstract
Methods and systems relate to enhancing heat transfer between a vessel wall and a sample or coupling medium during focused acoustic processing. The vessel containing the sample may include a heat exchanger on an inner surface and/or an outer surface of the vessel that can have any suitable shape or dimension that increases the surface area of the vessel wall. In some embodiments, heat exchanger features may disrupt a boundary layer of a liquid sample at the vessel wall during focused acoustic processing. Accordingly, the temperature of the liquid sample can be appropriately controlled. In some cases, heating and/or cooling of the liquid sample may be performed efficiently. In an embodiment, a liquid sample may be heated at a rate of at least about 25 degrees C. per ml per minute.
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