Phosphorylated NF45 Biomarkers, Antibodies And Methods Of Using Same

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United States of America Patent

APP PUB NO 20120021432A1
SERIAL NO

13087457

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Abstract

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The present invention relates to isolated phosphorylated NF45 peptides and isolated phosphorylation site-specific antibody or antigen-binding portion thereof that specifically binds a phosphorylated NF45 protein. The present invention also relates to methods of utilizing these antibodies to determine the therapeutic efficacy of a candidate compound and methods for screening for candidate compounds that increase the phosphorylation of NF45 protein in a cell.

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Patent Owner(s)

Patent OwnerAddress
ARQULE INC200 BOSTON AVENUE MEDFORD MA 02155

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chan, Thomas CK Winchester, US 5 21
Chen, Taiping Andover, US 2 11
Gu, Xiubin Wilmington, US 1 6
Waghorne, Carol Lexington, US 2 8
Yu, Yi Malden, US 261 4477
Zhao, Xiaolan Andover, US 5 7

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