Cobalamin Taxane Bioconjugates
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United States of America Patent
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Issued Date -
Jan 19, 2012
app pub date -
Jul 22, 2011
filing date -
Mar 19, 2007
priority date (Note) -
Abandoned
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Abstract
The present invention is directed to methods and compositions including a taxane covalently bonded to the cobalt atom of a cobalamin. The composition can be delivered by any effective route, but is particularly useful as an oral anti-cancer or antiangiogenic compound. The anti-cancer/anti-angiogenic compound can be used in various chemotherapies including anti-angiogenic chemotherapies, alone or in combination with other anti-cancer/anti-angiogenic compounds.
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