METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY

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United States of America Patent

APP PUB NO 20120015050A1
SERIAL NO

13164499

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Abstract

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This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM210 WEST 7TH STREET AUSTIN TX 78701
MYRIAD GENETICS INC322 NORTH 2200 WEST SALT LAKE CITY UT 84116

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abkevich, Victor Salt Lake City, US 31 178
Gutin, Alexander Salt Lake City, US 77 268
Lanchbury, Jerry Salt Lake City, US 32 196
Timms, Kirsten Salt Lake City, US 35 138

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