"Methods of Reducing Nephrotoxicity in Subjects Administered Nucleoside Phosphonates"
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United States of America Patent
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app pub date -
Apr 25, 2008
filing date -
Apr 27, 2007
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Abstract
A conjugate compound comprising an acyclic nucleoside phosphonate covalently coupled to a lipid for the therapeutic and/or prophylactic treatment of viral infection in an immunodeficient subject is described, along with compositions and methods of using the same. A preferred conugate compound is CMX001, having formula (I) or a pharmaceutically acceptable salt thereof.
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