Peg-albumin composition having at least one protected thiol region as a platform for medications
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United States of America Patent
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Issued Date -
Jan 12, 2012
app pub date -
Apr 2, 2010
filing date -
Apr 3, 2009
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Abstract
This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.
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