siRNA targeting cyclin-dependent kinase 4 (CDK4)

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United States of America Patent

APP PUB NO 20110319474A1
SERIAL NO

13199001

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Abstract

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Efficient sequence specific gene silencing for cyclin-dependent kinase 4 is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.

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Patent Owner(s)

Patent OwnerAddress
THERMO FISHER SCIENTIFIC INC81 WYMAN STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Khvorova, Anastasia Boulder, US 393 10160
Leake, Devin Denver, US 271 7128
Marshall, William Boulder, US 248 7212
Read, Steven Denver, US 219 4652
Reynolds, Angela Littleton, US 244 6997
Scaringe, Stephen Lafayette, US 232 6560

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