SELECTIVE M4 RECEPTOR ANTAGONIST AND ITS MEDICAL USE
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United States of America Patent
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Issued Date -
Dec 15, 2011
app pub date -
Nov 7, 2007
filing date -
Dec 30, 2006
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Abandoned
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Abstract
The present invention provides a selective M4 receptor antagonist, levorotatory demethylated phencynonate or its nontoxic pharmaceutically acceptable salt, a pharmaceutical composition comprising this compound, and a use thereof in the manufacture of a medicament for the treatment of motion dysfunction, such as, tremor, rigor and the like caused by Parkinson's disease (PD). The structure, of the compound is shown in Formula IIa:
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