Process for the manufacture of the calcium salt of rosuvastatin (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl](3R,5S)-3,5-Dihydroxyhept-6-enoic acid and crystalline intermediates thereof
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United States of America Patent
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Jun 21, 2016
Grant Date -
Dec 8, 2011
app pub date -
Jul 19, 2011
filing date -
Oct 24, 2003
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A process for the manufacture of the calcium salt of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid, useful as an HMGCoA reductase inhibitor, from a compound of the formula (7)
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
ASTRAZENECA UK LIMITED | 1 FRANCIS CRICK AVENUE CAMBRIDGE BIOMEDICAL CAMPUS CAMBRIDGE CB2 0AA |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Horbury, John | Bristol, GB | 8 | 100 |
# of filed Patents : 8 Total Citations : 100 | |||
Laffan, David Dermot Patrick | Macclesfield, GB | 6 | 73 |
# of filed Patents : 6 Total Citations : 73 | |||
Okada, Tetsuo | Osaka, JP | 22 | 230 |
# of filed Patents : 22 Total Citations : 230 |
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- 3 Citation Count
- C07D Class
- 36.67 % this patent is cited more than
- 9 Age
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