Selective Glycosidase Inhibitors and Uses Thereof
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United States of America Patent
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Issued Date -
Dec 8, 2011
app pub date -
Sep 16, 2009
filing date -
Sep 16, 2008
priority date (Note) -
Abandoned
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Abstract
The application relates to an immoalditol compound for selectively inhibiting glycosidases, a prodrug thereof and a pharmaceutical composition comprising the compound or the prodrug The application also relates to the use of the immoalditol compound for treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc Such diseases and disorders include neurodegenerative diseases, tauopathy, cancers, and cardiac disorders
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