SMALL MOLECULE PAK INHIBITORS

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United States of America Patent

APP PUB NO 20110294782A1
SERIAL NO

12514290

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides methods for treating fragile X syndrome and/or other neurodevelopmental disorders by administering small molecule p21-activated kinase (PAK) inhibitors to a patient suffering from, susceptible to, and/or exhibiting one or more symptoms of FXS and/or other neurodevelopmental disorders. The present invention provides specific small molecule PAK inhibitors and pharmaceutical compositions comprising small molecule PAK inhibitors.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hayashi, Mansuo L Winchester, US 2 3
Karaman, Mazen San Diego, US 1 0
Tonegawa, Susumu Chestnut Hill, US 21 181
Treiber, Daniel K San Diego, US 6 17
Zarrinkar, Patrick P San Diego, US 3 6

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