METHOD FOR DETERMINING IMMUNE SYSTEM ACTIVITY AND MEDICAMENT FOR INFLUENCING SAME
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United States of America Patent
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Issued Date -
Dec 1, 2011
app pub date -
May 2, 2011
filing date -
Apr 30, 2010
priority date (Note) -
Abandoned
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Abstract
A method for the determination of the state of the immune system, e.g. the state of activity and activation, respectively, of the immune system, using the determination of presence of a blood or peripheral mononuclear cell or plasma marker. The marker can be determined directly, e.g. by determination of its titre using a specific antibody against the marker, or indirectly, e.g. by the determination of the mRNA encoding the marker. Further, the invention relates to the use of the protein corresponding to the marker analysed in the analytical method, as a medicament, especially for influencing, e.g. for activating the immune system, more specifically for activating the cytotoxicity of NK cells as well as for activating the cytotoxicity and the proliferation of T-cells.
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