Preparation process for an inhibitor of a blood clotting factor

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United States of America Patent

APP PUB NO 20110288294A1
SERIAL NO

13107879

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Abstract

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The invention relates to a process for the preparation of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (I) from 5-chlorothiophene-2-carboxylic acid and 4-[4-((S)-5-aminomethyl-2-oxooxazolidin-3-yl)phenyl]morpholin-3-one (II)or a salt of this compound with a mineral acid or an organic acid in the presence of propanephosphonic anhydride.

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Patent Owner(s)

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ARCHIMICA GMBH65929 FRANKFURT AM MAIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jung, Joerg Floersheim, DE 15 112
Nonnenmacher, Michael Leimen, DE 4 4

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