FLUPIRTINE HYDROCHLORIDE MALEIC ACID COCRYSTAL
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United States of America Patent
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Issued Date -
Nov 10, 2011
app pub date -
Aug 6, 2009
filing date -
Aug 6, 2008
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Abandoned
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Abstract
The invention relates to crystalline forms of flupirtine, particularly to 1:1 flupirtine hydrochloride maleic acid cocrystal. The preparation and characterization of 1:1 flupirtine hydrochloride maleic acid cocrystal is described. The invention also relates to the therapeutic use of the flupirtine hydrochloride maleic acid cocrystal to treat nervous system disorders, pain disorders, and musculoskeletal disorders and to pharmaceutical compositions containing the cocrystal.
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