Use of CTGF as a Cardioprotectant
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United States of America Patent
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Issued Date -
Nov 10, 2011
app pub date -
Sep 17, 2009
filing date -
Sep 18, 2008
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Abstract
The present invention is based upon the surprising discovery that Connective Tissue Growth Factor (CTGF) may act directly on the heart as a cardioprotective factor and provides CTGF for use in the treatment of a subject who has incurred or is incurring damage to the heart, wherein said CTGF is for administration during or after the heart-damaging event. The invention also relates to CTGF for use in protection of the heart during or after surgery or during ex vivo transportation or storage of an explanted heart.
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