NANOPARTICLES OF BETA-LACTAM DERIVATIVES

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United States of America Patent

APP PUB NO 20110269731A1
SERIAL NO

13126756

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a complex made up of at least one beta-lactam molecule covalently bonded to at least one hydrocarbon radical including at least 18 carbon atoms and containing at least one unit of 2-methyl-buta-2-ene, to nanoparticles of said complexes, and to a method for preparing same, said complex and/or said nanoparticles optionally being in the form of a lyophilisate. The present invention also relates to a pharmaceutical composition including at least said complex and/or said nanoparticles. The invention finally relates to said complex and/or to said nanoparticles for the treatment and/or prevention of bacterial infections, in particular caused by strains that are sensitive to beta-lactams.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 RUE MICHEL-ANGE PARIS 75016
UNIVERSITE PARIS SUD15 AVENUE GEORGES CLEMENCEAU ORSAY 91400

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Couvreur, Patrick Villebon-sur-yvette, FR 40 743
Demaele, Didier Fresnes, FR 1 2
Zouhiri, Fatima Chatenay-malabry, FR 7 18

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