PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINE DERIVATIVE
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United States of America Patent
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Issued Date -
Oct 27, 2011
app pub date -
Sep 1, 2009
filing date -
Sep 1, 2008
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Abandoned
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Abstract
Optically active amine derivatives are produced by acting on imine derivatives with a culture of microorganisms having the ability to stereoselectively reduce the compounds, microbial cells, or processed products thereof, followed by collecting the generated optically active amine derivatives. Optically active amine derivatives obtained in the present invention are useful as materials for pharmaceutical agents. The present invention enables, for example, production of an optically active compound represented by formula (IV):(wherein R group represents an alkyl group having one to three carbon atoms; and n represents an integer of 1 to 4).
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