ASSESSMENT OF PROTEIN DEGRADATION BY MEASUREMENT OF ISOMERISED NEO-EPITOPE CONTAINING FRAGMENTS
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United States of America Patent
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Issued Date -
Oct 20, 2011
app pub date -
Nov 11, 2009
filing date -
Nov 13, 2008
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Abandoned
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Abstract
A method of immunoassay for fragments of a protein such as type II collagen in a biological sample detects fragments having a first epitope containing an isomerised amino acid residue and a second epitope generated by cleavage of the protein by the use of respective antibodies binding each of the two epitopes.
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