PHARMACEUTICAL COMPOSITION COMPRISING A BI-CYCLIC COMPOUND AND METHOD FOR STABILIZING THE BI-CYCLIC COMPOUND
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United States of America Patent
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Issued Date -
Oct 6, 2011
app pub date -
Jun 15, 2011
filing date -
Jan 24, 2006
priority date (Note) -
Abandoned
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Abstract
Disclosed is a method for stabilizing a pharmaceutically active bi-cyclic compound of formula (I):comprising the step of: admixing the same with a polyol and/or a fatty acid ester other than glyceride and a composition obtained by the method. In addition a soft gelatin capsule formulation of the compound of formula (I) obtained by incorporating the compound in a soft gelatin capsule shell comprising gelatin and a polyol plasticizer.
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