COMPOSITIONS OF A V-ATPASE INHIBITOR IN COMBINATION WITH A GLUCOCORTICOID RECEPTOR LIGAND AND METHODS OF USE

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United States of America Patent

APP PUB NO 20110237497A1
SERIAL NO

12949432

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Abstract

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A composition of a glucocorticoid receptor (GR) ligand, or analog thereof, and a V-ATPase inhibitor, or analog thereof. A method for administering such composition to a cell either to increase glucocorticoid transrepression activity or to increase glucocorticoid transactivation activity in the cell. Also, a method for treating a subject having an inflammatory or auto-immune disease by administering such composition.

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Patent Owner(s)

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VAN ANDEL RESEARCH INSTITUTE333 BOSTWICK AVENUE N E GRAND RAPIDS MI 49503

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  • 2010 Application Filing Year
  • A61K Class
  • 10962 Applications Filed
  • 7633 Patents Issued To-Date
  • 69.64 % Issued To-Date
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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Yuanzheng Grand Rapids, US 5 82
XU, HUAQIANG ERIC Grand Rapids, US 15 178
Xu, Yong Grand Rapids, US 250 1527

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  • 1 Citation Count
  • A61K Class
  • 10.68 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7424023113748323813073422412123001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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