TEMPERATURE SENSITIVE MUTANTS OF MATRIX METALLOPROTEASES AND USES THEREOF

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Nov 11, 2010
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Mar 5, 2010
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Mar 6, 2009

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Abstract

Provided are modified matrix metalloprotease (MMP) enzymes that exhibit temperature-dependent activity and uses thereof. The MMPs can be used, for example, to treat ECM-mediated diseases or disorders characterized by increased deposition or accumulation of one or more ECM components.

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HALOZYME, INC.

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Inventor Name	Address	# of filed Patents	Total Citations
Bookbinder, Louis	14823 Gable Ridge Rd	9	492
Chang, Hwai	1318 Shadow Hills Drive	5	140
Frey, Gerhard	13768 Via Cima Bella	107	962
Frost, Gregory	13662 Mercado Drive	1	57
Keller, Gilbert	2523 Carmelita Ave.	3	178
Short, Jay	12985 Via Esperia	23	217

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TEMPERATURE SENSITIVE MUTANTS OF MATRIX METALLOPROTEASES AND USES THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America Patent

12660894

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DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
September 22, 2011	US,20110229451,A2 US20110229451A2	REPUBLISHED PATENT APPLICATION
November 11, 2010	US,20100284995,A1 US20100284995A1	FIRST PUBLISHED PATENT APPLICATION

APP PUB NO	20100284995A1
SERIAL NO	12660894
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12660894

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