Substancefor Restoring Normal Co-expression and Interaction Between the LOX and NRAGE Proteins
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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N/A
Issued Date -
Sep 15, 2011
app pub date -
Oct 26, 2006
filing date -
Oct 28, 2005
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention relates to a substance for restoring normal co-expression and interaction between the LOX and NRAGE proteins.The invention relates in particular to the use of an effective amount of at least one substance that modulates the expression and/or activity of LOX of sequence ID no. 1, and/or that modulates the expression and/or activity of NRAGE of sequence ID no. 2, for the manufacture of a composition for modulating the interaction between the LOX and NRAGE proteins in order to regulate the balance between the cellular phenomena of proliferation, differentiation and apoptosis, particularly in cases where the balance between these phenomena is disturbed, and especially in cases where the interaction between LOX and NRAGE is absent or altered.The invention makes it possible especially to treat and/or prevent skin ageing, lichen planus, graft-versus-host reaction (GVH), eczema, psoriasis and a cancer, particularly an epithelial cancer and more particularly a cutaneous epithelial cancer, of basocellular or spinocellular type.
First Claim
Other Claims data not available