Compositions and Methods for Non-Targeted Activation of Endogenous Genes

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United States of America Patent

APP PUB NO 20110217779A1
SERIAL NO

13037742

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Abstract

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The present invention is directed generally to activating gene expression or causing over-expression of a gene by non-homologous or illegitimate recombination, of a regulatory sequence that causes expression of the gene. Thus, by the present invention, endogenous genes, including those associated with human disease and development, may be activated and isolated without prior knowledge of the sequence, structure, function, or expression profile of the genes.

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Patent Owner(s)

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ABT HOLDING COMPANYCLEVELAND OH 44115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HARRINGTON, JOHN J MENTOR, US 47 1220
RUNDLETT, STEPHEN COON RAPIDS, US 16 116
SCHERF, BRUCE STATE COLLEGE, US 1 0

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