C-TERMINAL EXON 5.4 OF RUNX1/AML1
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United States of America Patent
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Issued Date -
Sep 8, 2011
app pub date -
Jan 23, 2007
filing date -
Jan 23, 2006
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Abandoned
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Abstract
The present invention relates to a novel C-terminal exon of RUNX1/AML1, its nucleic acid sequence, its peptide and a full length amino acid sequence comprising the novel C-terminal exon. Furthermore, the invention is directed to an antibody against the C-terminal exon of RUNX1/AML1, a pharmaceutical composition for the treatment of various diseases, among others various tumours and the use of the C-terminal exon for the manufacture of a medicament. The C-terminal exon may also be used for the inhibition of cellular growth and/or induction of apoptosis. Furthermore, the invention relates to a method and a kit for diagnosing a disease, both using the C-terminal exon.
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