APPROACHES TO IDENTIFY LESS HARMFUL TOBACCO AND TOBACCO PRODUCTS

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United States of America Patent

SERIAL NO

13073811

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Abstract

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Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX.

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Patent Owner(s)

Patent OwnerAddress
VECTOR TOBACCO INCMORRISVILLE NC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albino, Anthony P New York, US 16 187
Darzynkiewicz, Zbigniew Chappaque, US 12 130
Jin, Wendy Chapel Hill, US 11 115
Jorgensen, Ellen D South Salem, US 6 24
Traganos, Frank Katonah, US 7 72

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