SYNTHETIC POLY D/L LYSINE FOR CONTROL OF DIRECTION AND RATE OF NEURITE GROWTH AND REGENERATION
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United States of America Patent
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Issued Date -
Sep 1, 2011
app pub date -
Nov 13, 2009
filing date -
Nov 14, 2008
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Abandoned
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Abstract
The present invention provides for use of poly-D/L-lysine (PLL) to control the growth of neural cells in vitro and in vivo. The invention describes the activity of defined PLL lines on neural cells and the ability to use the compound to control the direction and rate of growth of neurites on solid substrates. High-throughput screening assays are provided as are medical devices and therapies for treatment of neuronal injury or malfunction.
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