Treatment of Non-Neuronal Cancer using HSV-1 Variants

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United States of America Patent

SERIAL NO

13090983

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Abstract

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A mutant herpes simplex virus which has been modified in the γ34.5 gene such that the gene is non-functional is used to treat a non-neuronal cancer such as a mesothelioma, ovarian carcinoma, bladder cancer or melanoma. Typically, the mutant herpes simplex virus has been modified within the BamHI restriction fragment of the long terminal repeat of the viral genome.

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Patent Owner(s)

Patent OwnerAddress
VIRTTU BIOLOGICS LIMITEDNEWHOUSE LANARKSHIRE ML1 5UH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albelda, Steven Philadelphia, US 16 90
Brown, Susanne M Glasgow, GB 6 16
Fraser, Nigel W Philadelphia, US 6 6
Kaiser, Larry Philadelphia, US 4 111
Kucharczuk, John Philadelphia, US 3 2
Maclean, Alasdair R Glasgow, GB 6 16
Randazzo, Bruce P Philadelphia, US 3 2

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