COMPOSITIONS AND METHODS FOR MAKING ANDROSTENEDIONES
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United States of America Patent
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Issued Date -
Aug 4, 2011
app pub date -
Nov 13, 2008
filing date -
Nov 16, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention provides compositions and methods for producing androstenedione (4-androstenedione), of improved purity and for modulating its production, for example by deletion or inactivation of ksdA, cxgA, cxgB, cxgC, or cxgD. The invention also provides methods and compositions, including nucleic acids that encode enzymes, for producing 1,4-androstadiene-3,17-dione (ADD) and related pathway compounds, including 20-(hydroxymethyl)pregna-4-en-3-one and 20-(hydroxymethyl)pregna-1,4-dien-3-one. The compositions of the invention include nucleic acids, probes, vectors, cells, transgenic plants and seeds, transgenic animals, kits and arrays.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A01K:ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; ....
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- A01H:NEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT ....
- G06F:ELECTRIC DIGITAL DATA PROCESSING
- C40B:COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL ....
- C07K:PEPTIDES
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