METHODS FOR IDENTIFICATION AND USE OF AGENTS TARGETING CANCER STEM CELLS

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United States of America Patent

APP PUB NO 20110191868A1
SERIAL NO

12937070

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to methods for identifying compounds and compositions that target cancer stem cells. In some aspects, the invention relates to treatment methods that use compounds and compositions that specifically target cancer stem cells for inhibiting the growth and/or survival of cancer stem cells in a subject in need thereof. Other aspects of the invention relate to the use of cancer stem cell biomarkers in the selection of a treatment for inhibiting the growth and/or survival of cancer stem cells in a subject in need thereof.

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Patent Owner(s)

Patent OwnerAddress
PRESIDENT AND FELLOWS OF HARVARD COLLEGE17 QUINCY STREET CAMBRIDGE MA 02138
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH455 MAIN STREET CAMBRIDGE MA 02142

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gupta, Piyush Boston, US 458 2640
Lander, Eric S Cambridge, US 79 1197
Liao, Mai-Jing Winchester, US 3 20
Mani, Sendurai Houston, US 6 64
Onder, Tamer T Cambridge, US 5 22
Weinberg, Robert Brookline, US 13 135

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