5,6,6a,7,8,9-HEXAHYDRO-2H-PYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)
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United States of America Patent
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Issued Date -
Aug 4, 2011
app pub date -
Feb 4, 2011
filing date -
Feb 4, 2010
priority date (Note) -
Abandoned
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Abstract
Provided herein are compounds having the structure set forth in Formula (I):are as defined herein and methods of their synthesis. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
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