METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE

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United States of America Patent

SERIAL NO

11886385

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Abstract

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The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds.

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Patent Owner(s)

Patent OwnerAddress
THE BURNHAM INSTITUTELA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Houghten, Richard A San Diego, US 84 1963
Nefzi, Adel San Diego, US 27 222
Ostresh, John M San Diego, US 27 500
Pinilla, Clemencia San Diego, US 32 400
Reed, John C San Diego, US 151 1433
Welsh, Kate San Diego, US 8 111

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