ULTRASONIC MEASUREMENT OF pH IN FLUIDS
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United States of America Patent
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Issued Date -
Jul 21, 2011
app pub date -
Aug 4, 2009
filing date -
Aug 4, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention pertains to new methods and apparatuses for the determination of pH of a fluid. Applicants have discovered that ultrasonic spectrophonometry (the study and measurement of acoustic spectra) can be used to distinguish conformational changes of albumin and red blood cells in response to pH. In accordance with the present invention, there is provided a method of determining the pH of a fluid based on a pH-dependent conformation of at least one fluid constituent comprising subjecting the fluid to an ultrasonic pulse; detecting ultrasonic spectral data of the fluid constituent resulting from the ultrasonic pulse; wherein the spectral data varies with pH; and then calculating pH from the spectral data.
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