Method for Dedifferentiating Melanocytes
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United States of America Patent
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Issued Date -
Jul 21, 2011
app pub date -
Sep 30, 2009
filing date -
Oct 3, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention features a method for producing a dedifferentiated melanocyte. The method involves contacting a melanocyte with an agent that activates Notch1 and selecting for a dedifferentiated melanocyte which exhibits a premelanoma stem cell-like state. Agents for activating Notch1 and methods for using the cells and agents are also provided.
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