CLEAN GENOME BACTOFECTION

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United States of America Patent

SERIAL NO

13063450

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Abstract

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Methods for introducing and expressing genes in animal cells are provided comprising infecting the animal cells with live invasive reduced-genome bacteria comprising a eukaryotic expression cassette comprising said gene. Also provided are methods for producing a pluripotent stem (iPS) cell from a mammalian somatic cell comprising infecting the somatic cell with live invasive reduced-genome bacteria comprising one or more eukaryotic expression cassettes comprising at least a gene encoding the transcription factor Oct3/4 and a gene encoding a member of the SRY-related HMG-box (Sox) transcription factor family.

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Patent Owner(s)

Patent OwnerAddress
SCARAB GENOMICS LLCMADISON WI 53713

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blattner, Frederick R Madison, US 48 898
Burland, Val Cross plains, US 1 16
Landy, Charles Fitchburg, US 1 16
Shi, Nian-Qing Middleton, US 4 53
Stahl, Buffy Oregon, US 3 16

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