METHOD FOR THE FRACTIONATION OF KNOTWOOD EXTRACT AND USE OF A LIQUID-LIQUID EXTRACTION FOR PURIFICATION OF KNOTWOOD EXTRACT
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United States of America Patent
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Issued Date -
Jun 30, 2011
app pub date -
Jun 18, 2009
filing date -
Jul 1, 2008
priority date (Note) -
Abandoned
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Abstract
The invention relates to a method for the fractionation of knotwood extract, which has been obtained by extraction of knotwood with a hydrophilic solvent. The hydrophilic extract is extracted with a lipophilic solvent to remove lipophilic impurities. The invention also relates to the use of a liquid-liquid extraction for the purification of hydrophilic knotwood extract. The present process provides a purified knotwood extract, which contains more than 90% lignans, flavonoids and stilbenes and less than 10% impurities selected from resin acids, fatty acids, sterols, juvabiones, triglycerides and combinations thereof.
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