Specific ligands to sortilin
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United States of America Patent
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Feb 19, 2013
Grant Date -
Jun 30, 2011
app pub date -
Apr 27, 2009
filing date -
Apr 27, 2008
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Abstract
The present invention provides a Sortilin crystal and methods for growing said crystal. The invention furthermore provide methods for design of specific ligands based on the crystal structure of Sortilin. The present invention also relates to the preparation and use of such ligands for the preparation of a medicament for the treatment of disease, damage or disorders of the central and peripheral nervous systems.
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